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Furthermore, although carboplatin is a potential alternative to cisplatin in terms of efficacy, specific studies on these two drugs in NECs are lacking. In addition, biological affinity between SCLC and GEP-NECs is questionable because the latter group also includes large-cell histology. However, the few studies focusing on this regimen in SCLC did not evaluate it in GEP-NECs. 8 This drug combination is recommended by both European Neuroendocrine Tumor Society and North American Neuroendocrine Tumor Society guidelines. GEP-NECs are usually treated in a similar way to small-cell lung cancer (SCLC), ie, etoposide associated with platinum compounds such as cisplatin or carboplatin. 6 Although somatostatin analogs, targeted therapies and peptide radio receptor therapy play an important role in the management of metastatic (m)GEP-NETs, chemotherapy is the main therapeutic option for NECs and prognosis is poor, with a 2-year survival <20% and a median overall survival (mOS) of 5 months in a metastatic setting. Pancreatic NECs account for <1% of all pancreatic carcinomas, and <2%–3% of all pancreatic NENs. The incidence rate of colorectal NECs is 2:1,000,000, and is even lower for midgut/appendiceal sites. 3 – 5 However, they are called mixed adenoneuroendocrine carcinoma when at least 30% of either component is present. 2 The latter group includes small- and large-cell NECs and mixed components of adenocarcinoma or other non-neuroendocrine elements may also be associated with either of these NEC subtypes.
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World Health Organization (WHO) classification divides these neoplasms into three groups according to their Ki67% value: well-differentiated and moderately differentiated neuroendocrine tumors (NETs G1 and G2 NETs, respectively) for Ki67 ≤20% and neuroendocrine carcinomas (NECs) for Ki67 >20%. Paved spaces are numbered and assigned for the season.Neuroendocrine neoplasia (NEN) of the gastroenteropancreatic (GEP) tract is a heterogeneous group of malignancies. Your reserved space includes all Jaguar preseason, regular season and playoff games. Parking RentalĮvent parking located directly across the street from EverBank Field, WJCT’s parking lot is closest to the stadium, and amenities include the use of the climate-controlled indoor restroom facilities at WJCT, on-site security and…tailgating is encouraged!
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#Nero 2014 platinum elements series#
Whether it’s a short corporate video for your speaker’s bureau, a series of training tapes designed to bring your employees up to speed on a particular issue, WJCT has the experienced producers to make your project work.Ĭontact WJCT’s CreativeworX at (904) 358-6311. As the premier PBS facility for northeast Florida, WJCT will assist you and your corporation in developing and implementing a communications plan tailored to your specific internal and external needs. All of this for a daily rental cost that will fit your budget.Īdditionally, the television production capabilities of WJCT shouldn’t be overlooked. The brand new three-wall cyclorama, totaling 125 linear feet and measuring 23 feet tall, adds infinite flexibility to this already incomparable production facility.Īs the largest soundstage between Atlanta and Orlando, rental of Studio A also includes dressing rooms with showers, offices, access to wi-fi, food preparation and service areas and much more.
#Nero 2014 platinum elements full#
Over 7,800 square feet of unobstructed television and film production space, total environmental control, LED full color capsule lighting, 30-foot ceiling heights and more. You’ve never seen a facility quite like the WJCT Studio A Soundstage.